There are encouraging data for the treatment of wound infections with tea tree EO integrated into various functional dressings. For example, an electrospun polycaprolactone (PCL) nonwoven mat covered with a layer of chitosan and containing tea tree EO were produced and investigated in vitro [113]; tests proved that the mat effectively inhibited the growth of S. aureus. In vivo tests were performed by skin subtraction having dimensions of (1.2 1.2) cm2 on the back of the C57BL6/J mice in non-infected and infected animal models. After 7 days post-treatment, bacterial levels were found to be lower for the nonwoven mat with 10 μL concentration of tea tree EO-treated groups than the control: 81.6 18.1% and 93.7 9.57% decrease of bacterial contents, as compared to the control group [113]. Other studies synthesized films of chitosan loaded with different contents of tea tree EO droplets. The obtained films were tested in vitro against common wound pathogenic bacteria and fungi, S. aureus, E. coli and C. albicans, respectively. The present study reported that films exhibited antimicrobial activity against all strains and this activity is enhancing with the content of tea tree EO in films. Furthermore, films were non-toxic to L929 fibroblasts and sustained their growth [114].
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Digital rangefinders = The Leica M camera originates from 1925 and have been existing as film camera in many models. From 2006, the first Leica M digital rangefinder was launched, Leica M8. The Leica M7 (2002) is a film camera, so the new mode was Leia M8 and the main difference was that it had a crop digital sensor. The Next Leica M9 had a full-frame 24x36mm sensor. The Leica M240 had many features supposedly requested by users, the most noticeable was live view via a CMOS sensor, electronic viewfinder and video recording. Leica M10 was a return to the original Leica simplicity, including being a smaller body resembling the film cameras, and video and other features and buttons had been removed, a simplified menu created, and most noticeable an ISO dial to set the ISO on a wheel on the top left of the camera, very similar to the similar looking dial on older Leica film cameras where this dial was a rewind function for the film. Leica M11 (2022) was simplified even further, with a new sensor design that was designed to resemble classic color photography closer (Kodachrome and Leica M9 colors), yet featuring new technology such as triple-resolution sensor (where the sensor as a fourth function is also used as light meter), digital shutter and a new design where the battery is part of the bottom plate (no battery door, and no more bottom plate). 2ff7e9595c
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